1. Protocol for EZSPHERE®
1-1. Sato H, Idiris A, Miwa T, Kumagai H.
Vessels for Embryoid Body Formation and Rapid Differentiation of Pluripotent Stem Cells.
Scientific Reports 6, Article number: 31063 (2016)
doi:10.1038/srep31063
2. Stem Cell & Differentiation
2-1. Sugimura R, Jha DK, Han A, Soria-Valles C, da Rocha
EL, Lu YF, Goettel JA, Serrao E, Rowe RG, Malleshaiah M, Wong I, Sousa P, Zhu TN, Ditadi A, Keller G, Engelman AN, Snapper SB, Doulatov S, Daley GQ.Haematopoietic stem and progenitor cells from human pluripotent stem cells.
Nature (2017) doi:10.1038/nature22370
2-2. Aikawa N, Suzuki Y, Takaba K.
A Simple Protocol for the Myocardial Differentiation of Human iPS Cells.
Biological and Pharmaceutical Bulletin Vol. 38 (2015)
No.7 Pages 1070-1075
2-3. Zhang RR, Takebe T, Miyazaki L, Takayama M, Koike H, Kimura M, Enomura M, Zheng YW, Sekine K, Taniguchi H.
Efficient Hepatic Differentiation of Human Induced Pluripotent Stem Cells in a Three-Dimensional Microscale Culture.
Stem Cells and Tissue Repair Methods in Molecular Biology
Volume 1210, 2014, pp 131-141
2-4. Shimada H, Hashimoto Y, Nakada A, Shigeno K, Nakamura T.
Accelerated generation of human induced pluripotent stem cells with retroviral transduction and chemical inhibitors under physiological hypoxia.
Biochemical and Biophysical Research Communications,
Volume 417, Issue 2, Pages 659-664
2-5. Matsuura K, Seta H, Haraguchi Y, Alsayegh K, Sekine H, Shimizu T, Hagiwara N, Yamazaki K, Okano T.
TRPV-1-mediated elimination of residual iPS cells in bioengineered cardiac cell sheet tissues.
Scientific Reports 6, Article number: 21747 (2016)
doi:10.1038/srep21747
2-6. Miwa T , Idiris A, Kumagai H.
A novel cardiac differentiation method of a large number and uniformly-Sized spheroids using microfabricated culture vessels Regenerative Therapy, volume 15,
Pages18-26 (2020) NEW!
3. Cancer
3-1. Nakayama T, Otsuka S, Kobayashi T, Okajima H, Matsumoto K, Hagiya Y, Inoue K, Shuin T, Nakajima M, Tanaka T, Ogura SI.
Dormant cancer cells accumulate high protoporphyrin IX levels and are sensitive to 5-aminolevulinic acid-based photodynamic therapy Scientific Reports 6, Article
number: 36478 (2016) doi:10.1038/srep36478
3-2. Aihara A, Abe N, Saruhashi K, Kanaki T, Nishino T.
Novel 3-D cell culture system for in vitro evaluation of anticancer drugs under anchorage-independent conditions.
Cancer Science Volume 107, Issue 12 December 2016
Pages 1858–1866 DOI: 10.1111/cas.13095
3-3. Miyazaki K, Oyanagi J, Hoshino D, Togo S, Kumagai H, Miyagi Y.
Cancer cell migration on elongate protrusions of fibroblasts in collagen matrix.
Scientific Reports volume 9, Article number: 292 (2019)
doi: 10.1038/s41598-018-36646-z
3-4. Ohashi W, Yamamine N, Imura J, Hattori Y.
SKL2001 suppresses colon cancer spheroid growth through regulation of the E-cadherin/β-Catenin complex. Biochem
Biophys Res Commun. 2017 Nov 25;493(3):1342-1348.
doi: 10.1016/j.bbrc.2017.09.161.
3-5. Nakamura K, Komatsu M, Chiwaki F, Takeda T, Kobayashi Y, Banno K, Aoki D, Yoshida T, Sakai H
SIM21 attenuates resistance to hypoxia and tumor growth by transcriptional suppression of HIF1A in uterine cervical squamous cell carcinoma.
Scientific Reports 7, Article number: 14574(2017)
doi:10.1038/s41598-017-15261-4
3-6. Sawa A, Chiba T, Ishii J, Yamamoto H, Hara H, Kamma H
Effects of sorafenib and an adenylyl cyclase activator on in vitro growth of well-differentiated thyroid cancer cells.
Endocrine Journal Volume 64(2017) Issue 11 doi.
org/10.1507/endocrj.EJ16-0525
4. Organoid
4-1. Raja WK, Mungenast AE, Lin YT, Ko T, Abdurrob F, Seo J, Tsai LH.
Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer’s Disease Phenotypes.
PLOS ONE 11(9): e0161969. doi: 10.1371/journal.
pone.0161969
4-2. Onozato D, Yamashita M, Nakanishi A, Akagawa T, Kida Y, Ogawa I, Hashita T, Iwao T, Matsunaga T.
Generation of Intestinal Organoids Suitable for Pharmacokinetic Studies from Human Induced Pluripotent Stem Cells.
Drug Metab Dispos. 2018 Nov;46(11):1572-1580.
doi: 10.1124/dmd.118.080374. Epub 2018 Apr 3.
4-3. Koike H, Zhang RR, Ueno Y, Sekine K, Zheng YW, Takebe T, Taniguchi H.
Nutritional modulation of mouse and human liver bud growth through a branched-chain amino acid metabolism.
Development 2017 144: 1018-1024; doi: 10.1242/
dev.143032
4-4. Kano M, Suga H, Kasai T, Ozone C, Arima H.
Functional Pituitary Tissue Generation from Human Embryonic Stem Cells.
Curr Protoc Neurosci. 2018 Apr;83(1):e48.
doi: 10.1002/cpns.48.
4-5. Rachel A Heuer et al. Matsuoka Lab @Northwestern University
Three-Dimensional Otic Neuronal Progenitor Spheroids Derived from Human Embryonic Stem Cells.
Tissue Eng Part A., Online ahead of print. NEW!
5. Transplantation
5-1. Okumura H, Nanizawa E, Nakanishi A, Yukawa H, Hashita T, Iwao T, Baba Y, Ishikawa T, Matsunaga T.
Effective Transplantation of 2D and 3D Cultured Hepatocyte Spheroids Confirmed by Quantum Dot Imaging.
Advanced Biosystems. 2018, 2, 1800137.
Doi: 10.1002/adbi.201800137
